Consider four small molecules, A–D, which have the following binding affinities for a specific enzyme (these numbers are the equilibrium constants Kd for the dissociation of the enzyme/molecule complex). Which binds most tightly to the enzyme? Which binds least tightly?A) 4.5 μM

B) 13 nM

C) 8.2 pM

D) 6.9 mM

Answers

Answer 1
Answer:

Answer:

Binding affinity measures the strength of the interaction between a molecule to its ligand; it is expressed in terms of the equilibrium dissociation constant; and the higher value of this constant, the more weaker the binding between the molecule and the ligand is. On the other hand, small constans means that the interaction is tight. So "C" binds most tightly to the enzyme and "D" binds least tightly.


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You would like to make a 100 mL buffer solution at pH 8.00. Assuming you would like to accomplish this with a hypochlorous acid (HOCl) buffer (HOCl/NaOCl), Ka= 3.0 * 10-8. If the solution is 0.3 M in HOCl, what concentration of NaOCl would be necessary in the buffer solution to obtain a pH of 8.0?

Answers

Answer:

To obtain the pH of 8.0, the concentration of NaOCl needs to be 0.9 M in the 0.3 M HOCl solution

Explanation:

This problem can be solved by Henderson-Hasselbalch equation, which gives relation between the concentration of acid, its salt, pKa and the pH of the solution. This equation is given as,

pH=-log(K_a)+log([NaOCl])/([HOCl])

By placing the known variables in the above equation we get,

8=-log(3*10^(-8))+log([NaOCl])/(0.3)

8-7.52=log([NaOCl])/([0.3])

10^(0.48)=([NaOCl])/(0.3)

[NaOCl]=10^(0.48)*{0.3}

[NaOCl]=0.9 M

The above calculations show that the required concentration of NaOCl is 0.9 M.

A chemist prepares a solution of potassium permanganate (KMnO4) by measuring out 3.8 umol of potassium permanganate into a 100 mL volumetric flask and filling the flask to the mark with water. Calculate the concentration in mol/L of the chemist's potassium permanganate solution. Round your answer to 2 significant digits. x 5 ? Explanation Check

Answers

Answer:

3,8×10⁻⁵ mol/L of potassium permanganate solution

Explanation:

To calculate concentration in mol/L you must convert the 3,8 umol to moles and 100 mL to liters, knowing 1 umol are 1×10⁻⁶mol and 1L are 1000 mL.

3,8 umol × (1×10⁻⁶mol / 1 umol ) = 3,8×10⁻⁶mol of potassium permanganate.

100 mL × ( 1L / 1000 mL) = 0,100 L

Thus, concentration in mol/L is:

3,8×10⁻⁶mol / 0,100 L = 3,8×10⁻⁵ mol/L of potassium permanganate solution

I hope it helps!

What would be the effect on the observed melting point of sample were poorly packed?

Answers

if a sample is packed poorly, the sample will not heat evenly and will take longer to melt.

I will give Brainliest and 30 points to whoever answers first!

Answers

3,5, and 1 i think maybe i uhm yeah

You need to prepare a solution with a specific concentration of Na+Na+ ions; however, someone used the end of the stock solution of NaClNaCl, and there isn’t any NaClNaCl to be found in the lab. You do, however, have some Na2SO4Na2SO4. Can you substitute the same number of grams of Na2SO4Na2SO4 for the NaClNaCl in a solution? Why or why not?

Answers

Explanation:

Ionic equation

NaCl(aq) --> Na+(aq) + Cl-(aq)

Na2SO4(aq) --> 2Na+(aq) + SO4^2-(aq)

In NaCl solution, 1 mole of Na+ is dissociated in 1 liter of solution while in Na2SO4, 2 moles of Na+ is dissociated in 1 liter of solution.

Molecular weight of NA2SO4 = (23*2) + 32 + (16*4)

= 142 g/mol

Molecular weight of NaCl = 23 + 35.5

= 58.5 g/mol

Masses

% Mass of NA+ in Na2SO4 = mass of Na+/total mass of Na2SO4 * 100

= 46/142 * 100

= 32.4%

% Mass of NA+ in NaCl = mass of Na+/total mass of NaCl * 100

= 23/58.5 * 100

= 39.3%

Therefore, the % mass of Na+ in NaCl and Na2SO4 are different so it cannot be used.

Final answer:

You cannot substitute Na2SO4 directly for NaCl based on mass since they have different molar masses. The same mass of Na2SO4 will provide more Na+ ions than NaCl, leading to a change in the Na+ ion concentration.

Explanation:

No, you cannot substitute the same number of grams of Na2SO4 for the NaCl in a solution. This is because NaCl and Na2SO4 have different molar masses and therefore different numbers of moles per gram. The concentration of a solution is determined by the number of moles of solute per unit volume of solvent, not the mass. Hence, using the same mass of a different compound would alter the concentration of Na+ ions in the solution.

For instance, if one mole of NaCl gives us one mole of Na+, one mole of Na2SO4 will provide two moles of Na+. In other words, the same mass of Na2SO4 contains more Na+ ions than the same mass of NaCl. So using the same mass of Na2SO4 in place of NaCl will result in a solution with a higher Na+ ion concentration.

Learn more about Chemical Substitution here:

brainly.com/question/31649818

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Can anyone tell me about sulfuric acid in shampoo/soap?

Answers

The term sulfate is used in chemistry to denote a salt of sulfuric acid. ... This is the sulfate type which can be found in many cleaning and hygiene products including shampoos. The main reasons why it is added to shampoos are because this sulfate produces foam and is a powerful detergent.